The Role of Microglial Cells in the Spread of Alzheimer’s Disease

PURPOSE: Educational didactic illustration meant to tell the general story of how microglial cells may facilitate the spread of Alzheimer’s disease through the release of exosomes. Microglia release exosomes as an immune response to the amyloid plaque that builds up in a patient with Alzheimer’s, and those exosomes contain dangerous hyperphosphorylated tau protein. A series of more schematic and explanatory insets explain what tau protein is, the mechanism behind how microglia spread it, and its affect on the progression of Alzheimer’s.

SOFTWARE: Adobe Photoshop, Adobe Illustrator

DATE: 2018


Process Work

Soft Final

Initial Sketches

Initial Color Comp

Preliminary Sketches